| Protein Name | FERM domain containing kindlin 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10979 |
| Gene Symbol | FERMT2 |
| UniProt | Q96AC1 (FERM2_HUMAN), A0A024R687 (A0A024R687_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
57
Total Number of Articles : 47 |
Description |
FERM domain containing kindlin 2 |
| Gene Summary |
Enables several functions, including phosphatidylinositol-3,4,5-trisphosphate binding activity; protein serine/threonine kinase binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cellular component biogenesis; and positive regulation of intracellular signal transduction. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in several cellular components, including adherens junction; cytoplasmic side of plasma membrane; and focal adhesion. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |