Protein Name solute carrier family 5 member 8
Organism Homo sapiens
Gene ID 160728
Gene Symbol

SLC5A8

UniProt Q8N695 (SC5A8_HUMAN)
Relationships Total Number of functionally related compound(s) : 59
Total Number of Articles : 62
Description

solute carrier family 5 member 8

Gene Summary

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).[supplied by OMIM, Dec 2008]

synonyms
  • sodium-coupled monocarboxylate transporter 1
  • apical iodide transporter
  • electrogenic sodium monocarboxylate cotransporter
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Properties