| Protein Name | ALMS1, centrosome and basal body associated |
|---|---|
| Organism | Mus musculus |
| Gene ID | 236266 |
| Gene Symbol | Alms1 |
| UniProt | Q8K4E0 (ALMS1_MOUSE), A0A1D5RMI8 (A0A1D5RMI8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
18
Total Number of Articles : 13 |
Description |
ALMS1, centrosome and basal body associated |
| Gene Summary |
Enables alpha-actinin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cholesterol homeostasis; neuron development; and ovulation. Predicted to be located in ciliary basal body; mitochondrion; and nucleoplasm. Predicted to be active in centriole; centrosome; and cytosol. Is expressed in several structures, including aorta; central nervous system; genitourinary system; gut; and sensory organ. Used to study Alstrom syndrome and obesity. Human ortholog(s) of this gene implicated in Alstrom syndrome. Orthologous to human ALMS1 (ALMS1 centrosome and basal body associated protein). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |