Protein Name ER degradation enhancer, mannosidase alpha-like 1
Organism Danio rerio
Gene ID 394164
Gene Symbol

edem1

UniProt E9QJF1 (E9QJF1_DANRE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 2
Description

ER degradation enhancer, mannosidase alpha-like 1

Gene Summary

Predicted to enable calcium ion binding activity and mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in positive regulation of retrograde protein transport, ER to cytosol. Predicted to act upstream of or within carbohydrate metabolic process; protein alpha-1,2-demannosylation; and response to unfolded protein. Predicted to be located in endoplasmic reticulum membrane. Is expressed in anterior axial hypoblast; hatching gland; head; liver; and polster. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • ER degradation-enhancing alpha-mannosidase-like protein 1
  • zgc:55816
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Properties