| Protein Name | 3-hydroxy-3-methylglutaryl-CoA reductase b |
|---|---|
| Organism | Danio rerio |
| Gene ID | 541479 |
| Gene Symbol | hmgcrb |
| UniProt | Q58ER2 (Q58ER2_DANRE) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 4 |
Description |
3-hydroxy-3-methylglutaryl-CoA reductase b |
| Gene Summary |
Predicted to enable hydroxymethylglutaryl-CoA reductase (NADPH) activity. Acts upstream of or within circulatory system development; embryonic viscerocranium morphogenesis; and neural crest cell migration. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane and peroxisomal membrane. Is expressed in liver; notochord; and polster. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; coronary artery disease (multiple); diabetes mellitus (multiple); muscular disease (multiple); and neurodegenerative disease (multiple). Orthologous to human HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |