Protein Name solute carrier family 18 member A3
Organism Rattus norvegicus
Gene ID 60422
Gene Symbol

Slc18a3

UniProt Q62666 (VACHT_RAT)
Relationships Total Number of functionally related compound(s) : 99
Total Number of Articles : 97
Description

solute carrier family 18 member A3

Gene Summary

Enables acetylcholine:proton antiporter activity. Involved in acetylcholine uptake; neurotransmitter loading into synaptic vesicle; and response to ethanol. Located in axon terminus and synaptic vesicle. Part of AP-1 adaptor complex and AP-2 adaptor complex. Is active in cholinergic synapse; neuromuscular junction; and synaptic vesicle membrane. Biomarker of asthma and bladder disease. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 21. Orthologous to human SLC18A3 (solute carrier family 18 member A3). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • vesicular acetylcholine transporter
  • solute carrier family 18 (vesicular acetylcholine transporter), member 3
  • solute carrier family 18 (vesicular acetylcholine), member 3
Click to show/hide the synonyms
Properties