Protein Name islet amyloid polypeptide
Organism Homo sapiens
Gene ID 3375
Gene Symbol

IAPP

UniProt P10997 (IAPP_HUMAN), A0A024RAU1 (A0A024RAU1_HUMAN)
Relationships Total Number of functionally related compound(s) : 603
Total Number of Articles : 855
Description

islet amyloid polypeptide

Gene Summary

This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]

synonyms
  • islet amyloid polypeptide
  • Islet amyloid polypeptide (diabetes-associated peptide; amylin)
  • amylin
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Properties