| Protein Name | Vesicular monoamine transporter |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 3346192 |
| Gene Symbol | Vmat |
| UniProt | Q8IH57 (Q8IH57_DROME), Q86NW1 (Q86NW1_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
20
Total Number of Articles : 12 |
Description |
Vesicular monoamine transporter |
| Gene Summary |
Enables monoamine transmembrane transporter activity. Involved in several processes, including aminergic neurotransmitter loading into synaptic vesicle; cation transport; and positive regulation of dopaminergic neuron differentiation. Located in neuromuscular junction and synaptic vesicle. Is expressed in several structures, including adult head; central nervous system; larval ventral midline neurons; and ventral midline of embryo. Human ortholog(s) of this gene implicated in Parkinson's disease; bipolar disorder; schizophrenia; and type 1 diabetes mellitus. Orthologous to human SLC18A1 (solute carrier family 18 member A1) and SLC18A2 (solute carrier family 18 member A2). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |