| Protein Name | bromodomain containing 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14312 |
| Gene Symbol | Brd2 |
| UniProt | Q7JJ13 (BRD2_MOUSE), B2RS09 (B2RS09_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
28
Total Number of Articles : 19 |
Description |
bromodomain containing 2 |
| Gene Summary |
Enables acetylation-dependent protein binding activity and histone H4K12ac reader activity. Involved in several processes, including chromatin looping; positive regulation of T-helper 17 cell lineage commitment; and protein localization to chromatin. Acts upstream of or within neural tube closure. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; jaw; retina; and urinary system. Human ortholog(s) of this gene implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Orthologous to human BRD2 (bromodomain containing 2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |