Protein Name adenylate cyclase 1
Organism Mus musculus
Gene ID 432530
Gene Symbol

Adcy1

UniProt O88444 (ADCY1_MOUSE)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 86
Description

adenylate cyclase 1

Gene Summary

Enables adenylate cyclase activity. Involved in several processes, including modulation of chemical synaptic transmission; neuroinflammatory response; and positive regulation of CREB transcription factor activity. Acts upstream of or within axonogenesis and long-term memory. Located in cytoplasm and postsynaptic density. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • adenylate cyclase type 1
  • ATP pyrophosphate-lyase 1
  • Ca(2+)/calmodulin-activated adenylyl cyclase
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Properties