Protein Name phosphodiesterase 4A
Organism Rattus norvegicus
Gene ID 25638
Gene Symbol

Pde4a

UniProt P54748 (PDE4A_RAT)
Relationships Total Number of functionally related compound(s) : 22
Total Number of Articles : 20
Description

phosphodiesterase 4A

Gene Summary

Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity and cAMP binding activity. Involved in modulation of chemical synaptic transmission and response to xenobiotic stimulus. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Is active in Schaffer collateral - CA1 synapse. Biomarker of brucellosis and visual epilepsy. Orthologous to human PDE4A (phosphodiesterase 4A). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 3',5'-cyclic-AMP phosphodiesterase 4A
  • PDE4A10 cAMP phosphodiesterase
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
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Properties