| Protein Name | lysine demethylase 5B |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10765 |
| Gene Symbol | KDM5B |
| UniProt | Q9UGL1 (KDM5B_HUMAN), A0A3B3ITA8 (A0A3B3ITA8_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
76
Total Number of Articles : 69 |
Description |
lysine demethylase 5B |
| Gene Summary |
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016] |
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