| Protein Name | integrin alpha 2b |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16399 |
| Gene Symbol | Itga2b |
| UniProt | Q9QUM0 (ITA2B_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
71
Total Number of Articles : 59 |
Description |
integrin alpha 2b |
| Gene Summary |
Enables extracellular matrix binding activity. Acts upstream of or within cell-matrix adhesion. Located in external side of plasma membrane and focal adhesion. Is expressed in several structures, including early conceptus; hematopoietic system; liver; mesenchyme derived from splanchnopleure; and umbilical blood vessel. Used to study platelet-type bleeding disorder 16. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia; platelet-type bleeding disorder 16; thrombocytopenia; and von Willebrand's disease 1. Orthologous to human ITGA2B (integrin subunit alpha 2b). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |