Protein Name U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Organism Mus musculus
Gene ID 22185
Gene Symbol

U2af2

UniProt P26369 (U2AF2_MOUSE), Q80XR5 (Q80XR5_MOUSE)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2

Gene Summary

Enables C2H2 zinc finger domain binding activity. Involved in RNA splicing. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; U2-type spliceosomal complex; and U2AF complex. Predicted to be active in nuclear speck. Is expressed in several structures, including central nervous system; gut; liver lobe; lower urinary tract; and nose. Human ortholog(s) of this gene implicated in developmental delay, dysmorphic facies, and brain anomalies. Orthologous to human U2AF2 (U2 small nuclear RNA auxiliary factor 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • splicing factor U2AF 65 kDa subunit
  • U2 auxiliary factor 65 kDa subunit
  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa
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Properties