Protein Name E2F transcription factor 8
Organism Mus musculus
Gene ID 108961
Gene Symbol

E2f8

UniProt Q58FA4 (E2F8_MOUSE)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 8
Description

E2F transcription factor 8

Gene Summary

Enables DNA binding activity; DNA-binding transcription repressor activity; and identical protein binding activity. Involved in several processes, including hepatocyte differentiation; regulation of cell cycle process; and trophoblast giant cell differentiation. Acts upstream of or within fibroblast proliferation. Located in nucleus. Is expressed in central nervous system and retina. Orthologous to human E2F8 (E2F transcription factor 8). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • transcription factor E2F8
  • E2f family member 8
  • 4432406C08Rik
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Properties