| Protein Name | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20510 |
| Gene Symbol | Slc1a1 |
| UniProt | P51906 (EAA3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
67
Total Number of Articles : 79 |
Description |
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| Gene Summary |
Enables amino acid transmembrane transporter activity; identical protein binding activity; and monoatomic anion channel activity. Involved in several processes, including cell surface receptor signaling pathway; learning or memory; and nervous system development. Acts upstream of or within several processes, including behavioral fear response; cellular response to bisphenol A; and cellular response to mercury ion. Located in endosome membrane; membrane raft; and plasma membrane. Is active in several cellular components, including Schaffer collateral - CA1 synapse; apical plasma membrane; and recycling endosome. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Used to study dicarboxylic aminoaciduria and low tension glaucoma. Human ortholog(s) of this gene implicated in dicarboxylic aminoaciduria and schizophrenia 18. Orthologous to human SLC1A1 (solute carrier family 1 member 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |