Protein Name mutY DNA glycosylase
Organism Mus musculus
Gene ID 70603
Gene Symbol

Mutyh

UniProt Q99P21 (MUTYH_MOUSE), Q762D1 (Q762D1_MOUSE), Q762C9 (Q762C9_MOUSE)
Relationships Total Number of functionally related compound(s) : 45
Total Number of Articles : 36
Description

mutY DNA glycosylase

Gene Summary

Predicted to enable DNA N-glycosylase activity; DNA binding activity; and MutSalpha complex binding activity. Involved in negative regulation of necroptotic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • adenine DNA glycosylase
  • a/G-specific adenine DNA glycosylase
  • mMYH
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Properties