Protein Name sodium channel, voltage-gated, type XI, alpha
Organism Mus musculus
Gene ID 24046
Gene Symbol

Scn11a

UniProt Q9R053 (SCNBA_MOUSE)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 48
Description

sodium channel, voltage-gated, type XI, alpha

Gene Summary

Enables voltage-gated sodium channel activity. Involved in several processes, including behavioral response to chemical pain; detection of stimulus involved in sensory perception of pain; and monoatomic cation transmembrane transport. Acts upstream of or within establishment of localization in cell and sodium ion transport. Located in C-fiber and plasma membrane. Is active in axonal growth cone and neuronal cell body. Is expressed in several structures, including alimentary system; central nervous system; immune system; reproductive system; and sensory organ. Used to study familial episodic pain syndrome 3 and hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 3 and hereditary sensory and autonomic neuropathy type 7. Orthologous to human SCN11A (sodium voltage-gated channel alpha subunit 11). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • sodium channel protein type 11 subunit alpha
  • sensory neuron sodium channel 2
  • sodium channel protein type XI subunit alpha
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Properties