| Protein Name | myosin VI |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4646 |
| Gene Symbol | MYO6 |
| UniProt | Q9UM54 (MYO6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
31
Total Number of Articles : 47 |
Description |
myosin VI |
| Gene Summary |
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] |
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| Properties | |