Protein Name EPH receptor A4
Organism Homo sapiens
Gene ID 2043
Gene Symbol

EPHA4

UniProt P54764 (EPHA4_HUMAN), A1MA61 (A1MA61_HUMAN)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 55
Description

EPH receptor A4

Gene Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]

synonyms
  • ephrin type-A receptor 4
  • EPH-like kinase 8
  • TYRO1 protein tyrosine kinase
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Properties