Protein Name hypocretin (orexin) receptor 2
Organism Mus musculus
Gene ID 387285
Gene Symbol

Hcrtr2

UniProt P58308 (OX2R_MOUSE)
Relationships Total Number of functionally related compound(s) : 25
Total Number of Articles : 20
Description

hypocretin (orexin) receptor 2

Gene Summary

Enables orexin receptor activity. Involved in locomotion. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in nucleoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study narcolepsy. Orthologous to human HCRTR2 (hypocretin receptor 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • orexin receptor type 2
  • hypocretin receptor type 2
  • orexin receptor type-2a
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Properties