Protein Name insulin like growth factor binding protein 7
Organism Homo sapiens
Gene ID 3490
Gene Symbol


UniProt Q16270 (IBP7_HUMAN)
Relationships Total Number of functionally related compound(s) : 206
Total Number of Articles : 200

insulin like growth factor binding protein 7

Gene Summary

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]

  • insulin-like growth factor-binding protein 7
  • IGF-binding protein 7
  • IGFBP-rP1
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