Protein Name | cathepsin D |
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Organism | Homo sapiens |
Gene ID | 1509 |
Gene Symbol | CTSD |
UniProt | P07339 (CATD_HUMAN), V9HWI3 (V9HWI3_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
501
Total Number of Articles : 650 |
Description |
cathepsin D |
Gene Summary |
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015] |
synonyms |
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Properties | |