Protein Name nuclear receptor coactivator 1
Organism Rattus norvegicus
Gene ID 313929
Gene Symbol

Ncoa1

UniProt D4A3Q3 (D4A3Q3_RAT), A0A0G2JZG4 (A0A0G2JZG4_RAT)
Relationships Total Number of functionally related compound(s) : 27
Total Number of Articles : 28
Description

nuclear receptor coactivator 1

Gene Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; nuclear estrogen receptor binding activity; and nuclear retinoid X receptor binding activity. Involved in several processes, including brain development; estrous cycle; and lactation. Predicted to be located in several cellular components, including chromatin; cytosol; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Biomarker of hypothyroidism. Orthologous to human NCOA1 (nuclear receptor coactivator 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • nuclear receptor coactivator 1
  • steroid receptor coactivator 1
  • SRC-1
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Properties