| Protein Name | nuclear receptor co-repressor 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20602 |
| Gene Symbol | Ncor2 |
| UniProt | Q9WU42 (NCOR2_MOUSE), E9PY55 (E9PY55_MOUSE), F8VQL9 (F8VQL9_MOUSE), Q80ZV7 (Q80ZV7_MOUSE), E9Q9V3 (E9Q9V3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
25
Total Number of Articles : 24 |
Description |
nuclear receptor co-repressor 2 |
| Gene Summary |
Enables chromatin binding activity; sequence-specific double-stranded DNA binding activity; and transcription corepressor activity. Involved in several processes, including establishment of skin barrier; protein stabilization; and random inactivation of X chromosome. Acts upstream of or within several processes, including forebrain development; regulation of primary metabolic process; and type I pneumocyte differentiation. Located in nuclear body. Part of histone deacetylase complex. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; retina layer; and tooth. Used to study myelofibrosis. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |