Protein Name tumor necrosis factor b (TNF superfamily, member 2)
Organism Danio rerio
Gene ID 554167
Gene Symbol

tnfb

UniProt Q4W898 (Q4W898_DANRE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 6
Description

tumor necrosis factor b (TNF superfamily, member 2)

Gene Summary

Predicted to enable cytokine activity. Acts upstream of or within defense response to bacterium; immune response; and liver development. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Is expressed in several structures, including digestive system; heart; male organism; musculature system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to several human genes including LTA (lymphotoxin alpha). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF alpha
  • TNF-alpha 2
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Properties