Protein Name | integrin linked kinase |
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Organism | Mus musculus |
Gene ID | 16202 |
Gene Symbol | Ilk |
UniProt | O55222 (ILK_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
68
Total Number of Articles : 68 |
Description |
integrin linked kinase |
Gene Summary |
Predicted to enable several functions, including ATP binding activity; SH3 domain binding activity; and magnesium ion binding activity. Involved in several processes, including caveola assembly; integrin-mediated signaling pathway; and positive regulation of BMP signaling pathway. Acts upstream of or within several processes, including branching involved in ureteric bud morphogenesis; nervous system development; and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in focal adhesion and lamellipodium. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and retina. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ILK (integrin linked kinase). [provided by Alliance of Genome Resources, Jun 2025] |
synonyms |
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Properties | |