Protein Name autophagy related 14
Organism Homo sapiens
Gene ID 22863
Gene Symbol

ATG14

UniProt Q6ZNE5 (BAKOR_HUMAN)
Relationships Total Number of functionally related compound(s) : 44
Total Number of Articles : 49
Description

autophagy related 14

Gene Summary

Enables GTPase binding activity; membrane-membrane adaptor activity; and phosphatidylinositol 3-kinase inhibitor activity. Involved in several processes, including early endosome to late endosome transport; macroautophagy; and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Acts upstream of or within endosome to lysosome transport. Located in autophagosome and phagophore assembly site membrane. Is extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Part of phosphatidylinositol 3-kinase complex, class III. Is active in phagophore assembly site. [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • beclin 1-associated autophagy-related key regulator
  • ATG14 autophagy related 14 homolog
  • Beclin 1-Interacting protein
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Properties