| Protein Name | phosphatidylinositol kinase-related protein kinase TOR2 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 853632 |
| Gene Symbol | TOR2 |
| UniProt | P32600 (TOR2_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
20
Total Number of Articles : 23 |
Description |
phosphatidylinositol kinase-related protein kinase TOR2 |
| Gene Summary |
Enables protein serine/threonine kinase activity. Involved in several processes, including TOR signaling; establishment or maintenance of actin cytoskeleton polarity; and positive regulation of Rho protein signal transduction. Located in fungal-type vacuole membrane and plasma membrane. Part of TORC1 complex and TORC2 complex. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; kidney angiomyolipoma; lung disease (multiple); prostate cancer; and type 2 diabetes mellitus. Orthologous to human MTOR (mechanistic target of rapamycin kinase). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |