| Protein Name | mitofusin |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 852477 |
| Gene Symbol | FZO1 |
| UniProt | P38297 (FZO1_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
6
Total Number of Articles : 7 |
Description |
mitofusin |
| Gene Summary |
Enables GTPase activity and peroxisome-mitochondrion membrane tether activity. Involved in mitochondrial fusion. Acts upstream of or within intracellular distribution of mitochondria and mitochondrion inheritance. Located in mitochondrial outer membrane. Is active in peroxisomal-mitochondrial contact site and peroxisome. Used to study Charcot-Marie-Tooth disease type 2A2A and Charcot-Marie-Tooth disease type 2A2B. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease type 2A2A; Charcot-Marie-Tooth disease type 2A2B; Charcot-Marie-Tooth disease type 6; and multiple symmetric lipomatosis. Orthologous to human MFN2 (mitofusin 2). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
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| Properties | |