Protein Name phosphatidylinositol 3-kinase VPS34
Organism Saccharomyces cerevisiae S288C
Gene ID 850941
Gene Symbol

VPS34

UniProt P22543 (VPS34_YEAST)
Relationships Total Number of functionally related compound(s) : 28
Total Number of Articles : 47
Description

phosphatidylinositol 3-kinase VPS34

Gene Summary

Enables 1-phosphatidylinositol-3-kinase activity and protein kinase activity. Involved in several processes, including cellular response to potassium ion starvation; pexophagy; and positive regulation of transcription elongation by RNA polymerase II. Located in several cellular components, including fungal-type vacuole membrane; nucleus-vacuole junction; and phagophore assembly site. Part of phosphatidylinositol 3-kinase complex, class III, type I and phosphatidylinositol 3-kinase complex, class III, type II. Used to study Parkinson's disease. Orthologous to human PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • phosphatidylinositol 3-kinase VPS34
  • YLR240W
  • END12
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Properties