Protein Name protein kinase C, epsilon
Organism Rattus norvegicus
Gene ID 29340
Gene Symbol

Prkce

UniProt P09216 (KPCE_RAT), Q6DUV1 (Q6DUV1_RAT)
Relationships Total Number of functionally related compound(s) : 156
Total Number of Articles : 150
Description

protein kinase C, epsilon

Gene Summary

Enables several functions, including SH3 domain binding activity; protein kinase C activity; and protein kinase binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; negative regulation of mitochondrial calcium ion concentration; and negative regulation of mitochondrial membrane potential. Located in Golgi membrane; T-tubule; and cytosol. Is active in glutamatergic synapse; neuromuscular junction; and presynaptic cytosol. Used to study hypertension. Biomarker of type 2 diabetes mellitus. Orthologous to human PRKCE (protein kinase C epsilon). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • protein kinase C epsilon type
  • nPKC-epsilon
  • Pkce
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Properties