| Protein Name | protein kinase C, epsilon |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29340 |
| Gene Symbol | Prkce |
| UniProt | P09216 (KPCE_RAT), Q6DUV1 (Q6DUV1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
156
Total Number of Articles : 150 |
Description |
protein kinase C, epsilon |
| Gene Summary |
Enables several functions, including SH3 domain binding activity; diacylglycerol-dependent, calcium-independent serine/threonine kinase activity; and protein serine/threonine kinase binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; negative regulation of mitochondrial calcium ion concentration; and negative regulation of mitochondrial membrane potential. Located in Golgi membrane and T-tubule. Is active in glutamatergic synapse; neuromuscular junction; and presynaptic cytosol. Used to study hypertension. Biomarker of type 2 diabetes mellitus. Orthologous to human PRKCE (protein kinase C epsilon). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |