Protein Name | ATPase copper transporting beta |
---|---|
Organism | Rattus norvegicus |
Gene ID | 24218 |
Gene Symbol | Atp7b |
UniProt | Q9QUG4 (Q9QUG4_RAT), A0A0G2JWJ5 (A0A0G2JWJ5_RAT) |
Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 49 |
Description |
ATPase copper transporting beta |
Gene Summary |
Enables copper ion binding activity; copper ion transmembrane transporter activity; and zinc ion binding activity. Involved in several processes, including cellular response to metal ion; copper ion export; and lactation. Located in several cellular components, including basolateral plasma membrane; bicellular tight junction; and trans-Golgi network. Used to study Wilson disease; hepatitis; hepatocellular carcinoma; liver carcinoma; and renal adenoma. Human ortholog(s) of this gene implicated in Wilson disease. Orthologous to human ATP7B (ATPase copper transporting beta). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
|
Properties | |