| Protein Name | dishevelled binding antagonist of beta catenin 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 51339 |
| Gene Symbol | DACT1 |
| UniProt | Q9NYF0 (DACT1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
30
Total Number of Articles : 27 |
Description |
dishevelled binding antagonist of beta catenin 1 |
| Gene Summary |
The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
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