Protein Name dynein light chain roadblock-type 1
Organism Homo sapiens
Gene ID 83658
Gene Symbol

DYNLRB1

UniProt Q9NP97 (DLRB1_HUMAN), B4DFR2 (B4DFR2_HUMAN)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 21
Description

dynein light chain roadblock-type 1

Gene Summary

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

synonyms
  • dynein light chain roadblock-type 1
  • ROBL/LC7-like 1
  • bithoraxoid-like protein
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Properties