| Protein Name | SUV39H1 histone lysine methyltransferase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6839 |
| Gene Symbol | SUV39H1 |
| UniProt | O43463 (SUV91_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
72
Total Number of Articles : 110 |
Description |
SUV39H1 histone lysine methyltransferase |
| Gene Summary |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| synonyms |
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| Properties | |