Protein Name protein associated with LIN7 1, MAGUK p55 family member
Organism Homo sapiens
Gene ID 64398
Gene Symbol

PALS1

UniProt Q8N3R9 (PALS1_HUMAN), Q658X5 (Q658X5_HUMAN)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 12
Description

protein associated with LIN7 1, MAGUK p55 family member

Gene Summary

This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

synonyms
  • protein PALS1
  • MAGUK p55 subfamily member 5
  • membrane palmitoylated protein 5
Click to show/hide the synonyms
Properties