Protein Name | protein associated with LIN7 1, MAGUK p55 family member |
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Organism | Homo sapiens |
Gene ID | 64398 |
Gene Symbol | PALS1 |
UniProt | Q8N3R9 (PALS1_HUMAN), Q658X5 (Q658X5_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 12 |
Description |
protein associated with LIN7 1, MAGUK p55 family member |
Gene Summary |
This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
synonyms |
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Properties | |