Protein Name tripartite motif containing 22
Organism Homo sapiens
Gene ID 10346
Gene Symbol

TRIM22

UniProt Q8IYM9 (TRI22_HUMAN), B4DQS5 (B4DQS5_HUMAN)
Relationships Total Number of functionally related compound(s) : 28
Total Number of Articles : 17
Description

tripartite motif containing 22

Gene Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein is involved in innate immunity against different DNA and RNA viruses. [provided by RefSeq, Oct 2021]

synonyms
  • E3 ubiquitin-protein ligase TRIM22
  • 50 kDa-stimulated trans-acting factor
  • RING finger protein 94
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Properties