Protein Name MALT1 paracaspase
Organism Mus musculus
Gene ID 240354
Gene Symbol

Malt1

UniProt Q2TBA3 (MALT1_MOUSE)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 27
Description

MALT1 paracaspase

Gene Summary

Enables protease binding activity. Involved in several processes, including innate immune response; lipopolysaccharide-mediated signaling pathway; and positive regulation of immune response. Acts upstream of or within several processes, including B-1 B cell differentiation; positive regulation of NF-kappaB transcription factor activity; and regulation of T cell receptor signaling pathway. Located in cytosol. Part of polkadots. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in immunodeficiency 12; lymphoma; and non-Hodgkin lymphoma. Orthologous to human MALT1 (MALT1 paracaspase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
  • paracaspase-1
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Properties