Protein Name ATPase, H+ transporting, lysosomal accessory protein 2
Organism Mus musculus
Gene ID 70495
Gene Symbol

Atp6ap2

UniProt Q9CYN9 (RENR_MOUSE), Q1XID4 (Q1XID4_MOUSE)
Relationships Total Number of functionally related compound(s) : 57
Total Number of Articles : 60
Description

ATPase, H+ transporting, lysosomal accessory protein 2

Gene Summary

Predicted to enable signaling receptor activity. Involved in central nervous system maturation; positive regulation of Wnt signaling pathway; and synaptic vesicle lumen acidification. Located in endosome membrane and lysosomal membrane. Is expressed in brain; extraembryonic component; intestine; neural retina; and renal cortex. Human ortholog(s) of this gene implicated in X-linked parkinsonism-spasticity syndrome; congenital disorder of glycosylation type IIr; and syndromic X-linked intellectual disability Hedera type. Orthologous to human ATP6AP2 (ATPase H+ transporting accessory protein 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • renin receptor
  • ATPase H(+)-transporting lysosomal-interacting protein 2
  • ATPase, H+ transporting, lysosomal interacting protein 1
Click to show/hide the synonyms
Properties