CPRiL

Protein Name	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Organism	Homo sapiens
Gene ID	3284
Gene Symbol	HSD3B2
UniProt	P26439 (3BHS2_HUMAN), A0A024R0F9 (A0A024R0F9_HUMAN)
Relationships	Total Number of functionally related compound(s) : 63 Total Number of Articles : 82
Description	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Gene Summary	The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
synonyms	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 3 beta-HSD type II 3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II 3-beta-HSD II 3-beta-HSD adrenal and gonadal type 3-beta-hydroxy-5-ene steroid dehydrogenase 3-beta-hydroxy-Delta(5)-steroid dehydrogenase delta 5-delta 4-isomerase type II progesterone reductase short chain dehydrogenase/reductase family 11E, member 2 HSD3B HSDB SDR11E2 Click to show/hide the synonyms
Properties