Protein Name | ubiquitin C-terminal hydrolase L1 |
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Organism | Rattus norvegicus |
Gene ID | 29545 |
Gene Symbol | Uchl1 |
UniProt | Q00981 (UCHL1_RAT) |
Relationships |
Total Number of functionally related compound(s) :
48
Total Number of Articles : 50 |
Description |
ubiquitin C-terminal hydrolase L1 |
Gene Summary |
Predicted to enable several functions, including alpha-2A adrenergic receptor binding activity; cysteine-type peptidase activity; and ubiquitin protein ligase binding activity. Involved in sensory perception of pain and ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including neuron projection terminus; neuronal cell body; and nucleoplasm. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Biomarker of retinal disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia. Orthologous to human UCHL1 (ubiquitin C-terminal hydrolase L1). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |