| Protein Name | heme oxygenase 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3163 |
| Gene Symbol | HMOX2 |
| UniProt | P30519 (HMOX2_HUMAN), A0A087WT44 (A0A087WT44_HUMAN), B3KSE0 (B3KSE0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
541
Total Number of Articles : 503 |
Description |
heme oxygenase 2 |
| Gene Summary |
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
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