Protein Name bromodomain, testis-specific
Organism Mus musculus
Gene ID 114642
Gene Symbol

Brdt

UniProt Q91Y44 (BRDT_MOUSE), Q8BNZ8 (Q8BNZ8_MOUSE)
Relationships Total Number of functionally related compound(s) : 5
Total Number of Articles : 3
Description

bromodomain, testis-specific

Gene Summary

The protein encoded by this gene belongs to the BET protein family. BET proteins have two N-terminal bromodomains and one C-terminal extraterminal domain (ET domain). BET proteins regulate chromatin reorganization via binding to acetylated histones. This gene is thought to play a role in the transcriptional regulation of spermatogenesis. Although referred to as testis-specific bromodomain (Brdt) protein, RT-PCR indicates that this gene is expressed in both mouse oocytes and testes. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Jul 2008]

synonyms
  • bromodomain testis-specific protein
  • RING3-like protein
  • bromodomain-containing female sterile homeotic-like protein
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Properties