Protein Name | adhesion G protein-coupled receptor G1 |
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Organism | Homo sapiens |
Gene ID | 9289 |
Gene Symbol | ADGRG1 |
UniProt | Q9Y653 (AGRG1_HUMAN), A0A024R6U7 (A0A024R6U7_HUMAN), A0A0S2Z517 (A0A0S2Z517_HUMAN), B3KQN7 (B3KQN7_HUMAN), B3KQV4 (B3KQV4_HUMAN), B4DM06 (B4DM06_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
34
Total Number of Articles : 23 |
Description |
adhesion G protein-coupled receptor G1 |
Gene Summary |
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
synonyms |
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Properties | |