Protein Name adhesion G protein-coupled receptor G1
Organism Homo sapiens
Gene ID 9289
Gene Symbol

ADGRG1

UniProt Q9Y653 (AGRG1_HUMAN), A0A024R6U7 (A0A024R6U7_HUMAN), A0A0S2Z517 (A0A0S2Z517_HUMAN), B3KQN7 (B3KQN7_HUMAN), B3KQV4 (B3KQV4_HUMAN), B4DM06 (B4DM06_HUMAN)
Relationships Total Number of functionally related compound(s) : 34
Total Number of Articles : 23
Description

adhesion G protein-coupled receptor G1

Gene Summary

This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

synonyms
  • adhesion G-protein coupled receptor G1
  • 7-transmembrane protein with no EGF-like N-terminal domains-1
  • G protein-coupled receptor 56
Click to show/hide the synonyms
Properties