Protein Name fibroblast growth factor receptor substrate 2
Organism Homo sapiens
Gene ID 10818
Gene Symbol

FRS2

UniProt Q8WU20 (FRS2_HUMAN), L7RTG7 (L7RTG7_HUMAN)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 99
Description

fibroblast growth factor receptor substrate 2

Gene Summary

Enables fibroblast growth factor receptor binding activity and neurotrophin TRKA receptor binding activity. Involved in negative regulation of cardiac muscle cell differentiation. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in adherens junction. Biomarker of renal cell carcinoma. [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • fibroblast growth factor receptor substrate 2
  • FGFR signalling adaptor
  • FGFR substrate 2
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Properties