Protein Name heart and neural crest derivatives expressed 1
Organism Mus musculus
Gene ID 15110
Gene Symbol

Hand1

UniProt Q64279 (HAND1_MOUSE), Q5SQG1 (Q5SQG1_MOUSE)
Relationships Total Number of functionally related compound(s) : 18
Total Number of Articles : 16
Description

heart and neural crest derivatives expressed 1

Gene Summary

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; protein homodimerization activity; and transcription coregulator binding activity. Acts upstream of or within several processes, including animal organ development; mesoderm formation; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; heart and pericardium; and nervous system. Used to study hypoplastic left heart syndrome. Orthologous to human HAND1 (heart and neural crest derivatives expressed 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • heart- and neural crest derivatives-expressed protein 1
  • extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1
  • heart and neural crest derivatives expressed transcript 1
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Properties