Protein Name | mitogen-activated protein kinase kinase kinase 14 |
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Organism | Homo sapiens |
Gene ID | 9020 |
Gene Symbol | MAP3K14 |
UniProt | Q99558 (M3K14_HUMAN), Q68D39 (Q68D39_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
101
Total Number of Articles : 105 |
Description |
mitogen-activated protein kinase kinase kinase 14 |
Gene Summary |
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |