Protein Name Phorbol ester/diacylglycerol-binding protein unc-13;Protein kinase C
Organism Caenorhabditis elegans
Gene ID 172497
Gene Symbol

unc-13

UniProt P27715 (UNC13_CAEEL), A0A1C3NSH2 (A0A1C3NSH2_CAEEL), A0A1C3NSI0 (A0A1C3NSI0_CAEEL), G5EDN9 (G5EDN9_CAEEL), A0A1C3NSN5 (A0A1C3NSN5_CAEEL), A0A1C3NSJ3 (A0A1C3NSJ3_CAEEL), A0A1C3NSL4 (A0A1C3NSL4_CAEEL)
Relationships Total Number of functionally related compound(s) : 17
Total Number of Articles : 19
Description

Phorbol ester/diacylglycerol-binding protein unc-13;Protein kinase C

Gene Summary

Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in several processes, including positive regulation of oocyte development; regulation of oviposition; and regulation of pharyngeal pumping. Located in presynaptic active zone. Is expressed in nervous system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to several human genes including UNC13A (unc-13 homolog A) and UNC13B (unc-13 homolog B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • Phorbol ester/diacylglycerol-binding protein unc-13;Protein kinase C
  • CELE_ZK524.2
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Properties