Protein Name insulin like growth factor binding protein 6
Organism Homo sapiens
Gene ID 3489
Gene Symbol

IGFBP6

UniProt P24592 (IBP6_HUMAN)
Relationships Total Number of functionally related compound(s) : 88
Total Number of Articles : 71
Description

insulin like growth factor binding protein 6

Gene Summary

Enables identical protein binding activity and insulin-like growth factor II binding activity. Involved in cell migration and positive regulation of stress-activated MAPK cascade. Part of insulin-like growth factor binary complex. Implicated in obesity. Biomarker of breast cancer; in situ carcinoma; leiomyoma; and neovascular inflammatory vitreoretinopathy. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • insulin-like growth factor-binding protein 6
  • IBP-6
  • IGF binding protein 6
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Properties